Montreal Protocol was amended to completely phase out HFCs by 2047. This can prevent global temperature rise by 0.5 ºC. HFCs do not deplete the ozone layer but can cause greater global warming than carbon dioxide. Targets for reducing HFC use is different for developed and developing countries.  Developed countries like US have committed to reducing HFC use to 85% of 2011 levels. Baseline year for India and few other developing nations like Iran, Pakistan is 2024, while the reduction target of 85% and milestone year of 2047 remain the same. More than 190 countries gathered in Kigali, Rwanda, in October 2016 to sign the amendment during the 28th Meeting of Parties to Montreal Protocol.

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